Inflammation & Regeneration
In vivo detection of transcriptional regulation and migration of inflammatory and stem cells
The major long-term goals of the jointly executed research activities of the inflammation & regeneration programme within DiMI are:
- to investigate the role of gene regulation in models of inflammatory disease using;
- to bioluminescence imaging in transgenic reporter models;
- to develop novel transgenic reporter models for gene regulation and intracellular signalling;
- to establish novel and existing imaging probes specific for inflammation such as complement activation, immune cells and reactive oxygen species in animal models of inflammation;
- to develop technology for fluorescence imaging in deeper tissues;
- to clinical assessment of immune cell activation in patients with lung inflammatory disease.
