Paracelsus Medizinische Privatuniversität, Salzburg, Austria

Institute for Molecular Regenerative Medicine

[Group description | Scientific staff | Publications within DiMI]

References

  1. Couillard-Despres S., Wuertinger C., Kandasamy M., Caioni M., Stadler K., Aigner R., Bogdahn U., Aigner L. (2009) Ageing Abolishes the Effects of Fluoxetine on Neurogenesis. Mol. Psychiatry. Jan 13. [Epub ahead of print]
  2. Ramm P, Couillard-Despres S, Plötz S, Rivera FJ, Krampert M, Lehner B, Kremer W, Bogdahn U, Kalbitzer HR, Aigner L. (2008) A NMR Biomarker for Neural Progenitor Cells: Is It All Neurogenesis? Stem Cells 2008 Nov 6. [Epub ahead of print].
  3. Rivera FJ, Kandasamy M, Couillard-Despres S, Caioni M, Sanchez R, Huber C, Weidner N, Bogdahn U, Aigner L. (2008) Oligodendrogenesis of Adult Neural Progenitors: Differential Effects of Ciliary Neurotrophic Factor and Mesenchymal Stem Cell Derived Factors. J Neurochem. 107(3):832-43.
  4. Mueller AM, Pedré X, Stempfl T, Kleiter I, Couillard-Despres S, Aigner L, Giegerich G, Steinbrecher A. (2008) Novel role for SLPI in MOG-induced EAE revealed by spinal cord expression analysis. J Neuroinflammation. 5: 20.
  5. Ladewig J, Koch P, Endl E, Meiners B, Opitz T, Couillard-Despres S, Aigner L, Brüstle O. (2008) Lineage Selection of Functional and Cryopreservable Human Embryonic Stem Cell-Derived Neurons. Stem Cells. 26(7):1705-12.
  6. Couillard-Després S., Winner B., Plötz S., Wiedermann D., Aigner R., Bogdahn U., Winkler J., Hoehn M., Aigner L. (2008) In vivo optical imaging of neurogenesis - Watching new neurons in the intact brain. Molecular Imaging. 7(1): 28-34.
  7. Couillard-Despres S., Quehl E., Karl C., Ploetz S., Bogdahn U., Winkler J., Aigner L. (2008) In vitro reporter model of neuronal development and early differentiation processes. BMC Neuroscience. 9: 31.
  8. Winner B., Couillard-Despres S., Geyer M., Aigner R., Bogdahn U., Aigner L., Kuhn G., Winkler J. (2008). Dopamiergic lesion enhances growh factor-induced striatal neuroblast migration. J Neuropath Exp Neurol, 67(2): 105-16.
  9. Aigner L. & Bogdahn U. (2008) TGF-beta in neural stem cells and in tumors of the central nervous system. Cell Tissue Res. 331(1): 225-41.
  10. Hehr U, Uyanik G, Gross C, Walter MC, Bohring A, Cohen M, Oehl-Jaschkowitz B, Bird LM, Shamdeen GM, Bogdahn U, Schuierer G, Topaloglu H, Aigner L, Lochmuller H, Winkler J (2007) Novel POMGnT1 mutations define broader phenotypic spectrum of muscle-eye-brain disease. Neurogenetics. 8(4): 279-88.
  11. Beier, D., Hau, P., Proescholdt, M., Lohmeier, A., Wischhusen, J., Oefner, P.J., Aigner, L., Brawanski, A., Bogdahn, U. & Beier, C.P. (2007) CD133(+) and CD133(-) glioblastoma-derived cancer stem cells show differential growth characteristics and molecular profiles. Cancer Res, 67: 4010-4015.
  12. Kohl, Z., Kandasamy, M., Winner, B., Aigner, R., Gross, C., Couillard-Despres, S., Bogdahn, U., Aigner, L. & Winkler, J. (2007) Physical activity fails to rescue hippocampal neurogenesis deficits in the R6/2 mouse model of Huntington's disease. Brain Res, 1155: 24-33.
  13. Uyanik, G., Morris-Rosendahl, D.J., Stiegler, J., Klapecki, J., Gross, C., Berman, Y., Martin, P., Dey, L., Spranger, S., Korenke, G.C., Schreyer, I., Hertzberg, C., Neumann, T.E., Burkart, P., Spaich, C., Meng, M., Holthausen, H., Ades, L., Seidel, J., Mangold, E., Buyse, G., Meinecke, P., Schara, U., Zeschnigk, C., Muller, D., Helland, G., Schulze, B., Wright, M.L., Kortge-Jung, S., Hehr, A., Bogdahn, U., Schuierer, G., Kohlhase, J., Aigner, L., Wolff, G., Hehr, U. & Winkler, J. (2007) Location and type of mutation in the LIS1 gene do not predict phenotypic severity. Neurology, 69: 442-447.
  14. Couillard-Despres S., Winner B., Karl C., Lindemann G., Schmid P., Aigner R., Laemke J., Bogdahn U., Winkler J., Bischofberger J., Aigner L. (2006). Targeted transgene expression in neuronal precursors: watching young neurons in the old brain. European Journal of Neuroscience. 24(6): 1535-45.
  15. Rivera F., Couillard-Despres S., Pedre-Villareal X., Ploetz S., Lois C., Bogdahn U., Aigner L. (2006). Mesenchymal stem cells instruct oligodendrogenic fate decision on adult neural stem cells. Stem Cells. 24(10): 2209-19.
  16. Rivera F., Sierralta W.D., Minguell J., Aigner L. (2006). Adult hippocampus derived soluble factors induce a neuronal-like phenotype in mesenchymal stem cells. Neuroscience Letters. 406: 49-54.
  17. Pfeifer K., Vroemen M., Caioni M., Aigner L., Bogdahn U., Weidner N. (2006). Autologous adult neural progenitor cell transplantation represents a feasible strategy to promote structural repair in the chronically injured spinal cord. Regenerative Medicine. 1(2): 255-66.
  18. Wachs F.-P., Winner B., Couillard-Despres S., Schiller T., Aigner R., Winkler J., Bogdahn U., and Aigner L. (2006). Transforming growth factor-b1 is a negative modulator of adult neurogenesis. J. Neuropath. Exp. Neurol. 65(4): 358-70.
  19. Winner B., Geyer M., Couillard-Despres S., Aigner R., Bogdahn U., Aigner L., Kuhn G., Winkler J. (2006). Striatal deafferentation increases dopaminergic neurogenesis in the adult olfactory bulb. Exp Neurol. 197: 113-21.
  20. Engelhardt M., Bogdahn U., Aigner L. (2005). Adult retinal pigment epithelium cells express neural progenitor properties and the neuronal precursor protein doublecortin. Brain Res, 1040: 98-111.
  21. Couillard-Despres S., Winner B., Schaubeck S., Aigner R., Vroemen M., Weidner N., Bogdahn U., Winkler J., Kuhn H.-G., Aigner L. (2005). Doublecortin expression levels in adult brain reflect neurogenesis. Eur. J. Neurosci, 21: 1-14. 
  22. Karl C., Couillard-Despres S., Prang P., Munding M., Kilb W., Brigadski T., Plötz S., Mages W., Luhmann H., Winkler J., Bogdahn U., Aigner L. (2005). Neuronal precursor specific activity of a human doublecortin regulatory sequence. J. Neurochem, 92: 264-282.
  23. Winner B., Lie C., Rockenstein E., Aigner R., Aigner L., Masliah E., Kuhn H.-G., Winkler J. (2004). Human wild-type a-synuclein impairs neurogenesis. J. Neuropath. Exp. Neurol., 63: 1155-1166.
  24. Schänzer A., Wachs F.-P., Wilhelm D., Acker T., Cooper-Kuhn C., Beck H., Winkler J., Aigner L., Plate K.H., Kuhn H.G. (2004). Direct stimulation of adult neural stem cells in vitro and neurogenesis in vivo by vascular endothelial growth factor. Brain Pathology, 14: 237-248.
  25. Couillard-Despres S., Uyanik G., Ploetz S., Karl C., Stefan H., Winkler J., Aigner L. (2004). Mitotic impairment by doublecortin is diminished by doublecortin mutations found in patients. Neurogenetics. 5: 83-93.
  26. Engelhardt M., Wachs F.-P., Couillard-Despres S., Aigner L. (2004). The neurogenic competence of progenitors from the postnatal retina in vitro. Experimental Eye Research, 8: 1025-36.
  27. Lange M., Winner B., Müller J.L., Marienhagen J., Schröder M., Aigner L., Uyanik G., Winkler J. (2004). Functional imaging in PNH caused by a new filamin A mutation. Neurology, 62: 151-2.
  28. Vroemen M., Aigner L., Winkler J., Weidner N. (2003). Adult neural progenitor cell grafts survive after acute spinal cord injury and integrate into axonal pathways. European Journal of Neuroscience, 18: 743-51.
  29. Brown J., Couillard-Despres S., Cooper-Kuhn C., Winkler J., Aigner L., Kuhn H.-G. (2003). Transient expression of doublecortin during adult neurogenesis. Journal of Comparative Neurology, 467: 1-10.
  30. Uyanik G., Aigner L., Martin P., Hehr U., Gross C., Marschner-Schaefer H., Winkler J. (2003). ARX mutations in X-linked lissencephaly with ambiguous genitalia (XLAG). Neurology, 61: 232-235.
  31. Wachs F.-P., Couillard-Despres S., Engelhardt M., Wilhelm D., Ploetz S., Vroemen M., Kaesbauer J., Uyanik G., Klucken J., Karl C., Tebbing J., Svendsen C.N., Weidner N., Kuhn H.-G., Winkler J., Aigner L. (2003). High efficacy of clonal growth and expansion of adult neural stem cells. Lab. Invest., 83: 949-962.
  32. Aigner L., Uyanik G., Couillard-Despres S., Ploetz S., Wolff G., Morris-Rosendahl D, Martin P., Eckel J., Spranger S., Otte J., Woerle H., Holthausen H., Apheshiotis N., Flügel D., Winkler J. (2003). Somatic mosaicism and variable penetrance in Doublecortin-associated migration disorders. Neurology, 60: 329-332.